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Mal-Propionyl-PEG6-Gly-Gly-Phe-Gly-PAB(m-PEG4) mmae DOTA bifucational chelator containing an

SKU: 12914069975

4.3
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Description

DOTA bifucational chelator containing an amine group

Product Name Thalidomide-O-acetamido-C3-azide Synonyms Thalidomide-4'-O-acetamido-C3-azide CAS Number n/a Related CAS Molecular Formula C18H18N6O6 Molecular Weight 414

Bioconjugate Chemistry

BG-Ac is a SNAP-tag substrate used as a small-sized label for comparison with other SNAP-tag substrates

Mal-Propionyl-PEG6-Gly-Gly-Phe-Gly-PAB(m-PEG4) mmae DOTA bifucational chelator containing anSOLU KNEX cleavable linker features a Gly Gly Phe Gly (GGFG) peptide. The conventional maleimidocaproyl (MC) unit is replaced by Mal Propionyl PEG6 moiety to enhance aqueous solubility. The Mal Propionyl group may also improve retro Michael addition stability during antibody conjugation. m PEG4 is attached to the commonly used self immolative para aminobenzyl (PAB) moiety to increase aqueous solubility. Derived from established ADC linker

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